标签：功能 mamicode repeat sed 组成 bsp 图片 data bit
缠绕上去，就形成核小体了。每个组蛋白肽链都有氮端和碳端两个“尾巴”，这些“尾巴”上的氨基酸可以被加上一些化学基团，即“修饰”。
绿色 = 通常具有转录活性区；
红色 = 通常具有转录抑制区；
黑色 = 其他功能。
| Histone mark | Where to find it | Antibody |
| H3K4me1 | Active enhancers | ab176877 |
| H3K4me3 | Promoters of active genes, bivalent domains | ab8580 |
| H3K9ac | Active enhancers and promoters | ab177177 |
| H3K27ac | Active enhancers and promoters | ab177178 |
| H3K36me3 | Transcribed regions | ab9050 |
| H3K79me2 | Transcribed regions | ab177184 |
| H3K9me3 | Heterochromatin, satellite repeats, gene-poor regions | ab176916 |
| H3K27me3 | Repressed promoters in gene-rich regions, developmental regulators, bivalent domains | ab192985 |
| Gamma H2A.X | DNA double-strand breaks | ab81299 |
| H3S10P | Whole chromosomes in mitosis | ab177218 |
| H4K16ac | Reduced in cancer at repetitive sequences, active genes and enhancers in ESCs. Inhibits formation of high order chromatin structure. | ab109463 |
（From https://www.abcam.cn/epigenetics/histone-modifications-and-where-to-find-them-2）
标签：功能 mamicode repeat sed 组成 bsp 图片 data bit
原文地址：https://www.cnblogs.com/emanlee/p/12342630.html
