修改该列item的flags. 例如:

#include <QApplication>
#include <QTableWidget>
#include <QTableWidgetItem>
int main(int argc, char **argv)
{
    QApplication app(argc, argv);
    int col = 0;
    QTableWidget *table = new QTableWidget(5, 3);
    table->setItem(0, col, new QTableWidgetItem(QString("test")));
    int i;
    for(i = 0; i < table->rowCount(); i++){
        QTableWidgetItem *item = table->item(i, col);
        if(item) {
            item->setFlags(item->flags() & (~Qt::ItemIsEditable));
        } else {
            item = new QTableWidgetItem;
            item->setFlags(item->flags() & (~Qt::ItemIsEditable));
            table->setItem(i, col, item);
        }
    }
    table->show();
    return app.exec();
}